The cast includes Matthew Law, Y'lan Noel, Cleopatra Coleman, Tre Hale, Domenick Lombardozzi, Jonnie Park, Ariana Guerra, Gabrielle Dennis, Michael Potts, Sophina Brown, Cedric Joe, and Jeff Pierre.

Nemesis is the story of two men on either side of the law, the tale of what happens when Coltrane Wilder (Noel), an unstoppable force (an expert criminal) meets an immovable object (a brilliant police detective), Isaiah Stiles (Law). What starts as a series that aims to subvert the heist genre at every turn, amped with thrilling life-or-death stakes, family dynamics and explosive action, actually gives birth to an exploration of what drives us, sustains us, and ultimately destroys us.